After that, the selected studies were considered high quality with a score above 3 out of 5. The methodological quality of each study was evaluated using the Jadad scale, a 5-point scale which assignes scores for reported randomization, blinding, and withdrawals . Unpublished documents, review studies, conference abstracts, theses, book chapters, comments, and response articles were excluded. Further details about study eligibility and the selection process are shown in Table 2 (PICOS framework) and in the PRISMA flowchart diagram (Figure 1).
The results were promising for women too - all but one of these women with very low libidos reported better sexual desire after taking 500–1,500 mg for 90 days . The most intriguing aspect of Tribulus terrestris research lies in how differently it affects libido versus hormone levels. However, it might help those dealing with age-related testosterone decline or clinical hypogonadism. Men with normal hormone levels won't benefit much from TT. In fact, eight out of ten studies found no real changes in androgen profiles after TT supplementation . Clinical studies reveal some interesting facts about who might benefit from this supplement and when.
Despite inconclusive evidence for TT supplementation as a testosterone booster, TT presented advantageous effects for patients suffering from ED in 3 of the 5 studies 9,19,21. The present systematic review evaluated the effects of TT supplementation on testosterone levels and ED. Of these, two studies 9,21 supported an increase in testosterone levels; they included men suffering from hypogonadism.
Two studies found modest increases in total testosterone (60–70 ng/dL) in men with hypogonadism . The message is clear - men with normal hormone levels won't see much benefit from TT as a testosterone booster. Animal studies show testosterone increases with TT, but these results don't carry over to humans . Science tells us that Tribulus terrestris (TT) supplements don't boost testosterone in most men.
Given the relevance of the topic and the recent studies showing promising results regarding the potential benefits of TT supplementation for ED , the present study aimed to summarize the literature about the effects of TT supplementation on testosterone levels and erectile dysfunction. Zygophyllaceae (TT) is a plant that has been claimed to increase testosterone levels and improve sexual function, particularly erectile dysfunction, with potential benefits for male sexual health. A pilot study of ageing males with partial androgen deficiency and erectile dysfunction showed better testosterone levels and erectile function after taking TT supplements . Although its extract has been used as a dietary supplement since the 1980s in belief that it increases testosterone levels to aid body building or sexual enhancement in men, T.
Furthermore, Kamenov et al. revealed that 500 mg/d of TT supplementation over the course of 3 months improved IIEF-5 scores as well as intercourse satisfaction, sexual desire, orgasmic function, overall satisfaction, and global efficacy questionnaire (GEQ) responses. Furthermore, this study reported benefits of TT supplementation on semen analysis and safety at an uncommonly high dosage. In general, both TT and placebo groups had improved parameters of ED, penile weakness and loss of rigidity, and premature ejaculation, while testosterone levels did not change significantly. Overall, TT supplementation improved erectile function in men with ED.
Yet its effect on testosterone levels remains up for debate. As with all supplements, you should consider the potential benefits and risks before taking Tribulus terrestris. And although it doesn’t increase testosterone, Tribulus terrestris may improve libido in men and women. In humans, there is some evidence that it may improve blood sugar control and cholesterol levels in people with type 2 diabetes. Overall, the majority of studies do not show that this supplement has harmful side effects. However, by the end of the study, there were no differences in improvements in strength or body composition between the supplement and placebo groups (14).
Thus, further well-controlled, randomized clinical trials are warranted to establish an effective TT supplementation protocol (dosage and duration) to improve erectile function. Therefore, further well-controlled clinical trials are imperative to portray reliable conclusions about TT supplementation in the field of male health and hence to afford qualified trials for future meta-analysis studies. At best, TT is a low-cost supplement and well-tolerated at the documented dosage regimens, as no clinical side effects or impairment in lipid or liver panel tests were registered in the studies (Table 3), revealing the potential safety of TT supplementation . It is worth mentioning that saponin concentration differed from 40 to 60% of TT supplements between the included studies, with the exception of the study by Santos et al. , which reported no details of saponin content. Regardless of this concern, such a testosterone increase is equivalent to the potential of vitamin D supplementation and some herbals supplements, such as long Jack (Eurycoma longifolia Jack, Simaroubaceae) and fenugreek (Trigonella foenum-graceum L., Fabaceae) 5,25.
One study had people take 500 mg of extract with 225 mg of furostanol saponins three times each day . Higher saponin percentages mean you need smaller doses because the supplement is stronger . This percentage shows how strong the supplement is—a vital detail when you're buying. Some studies used smaller amounts of 500–750 mg/day for 4–8 weeks .. In both studies, subjects received 3 capsules daily (750 mg) of TT (Trib Gold, origin Bulgaria, 250 mg of TT and a minimum of 45% of saponins per capsule) over the course of 3 months. Concerning the main outcomes, all studies investigated the effects of TT supplementation on serum androgen levels. Zygophyllaceae (TT) has been used for centuries, mainly in India and China, as an herbal medicine and as a sexual stimulant to treat ED and augment testosterone levels. It is good to know that there are many testosterone-boosting supplements out on the market which is made up of high-quality all-natural ingredients.|Thus, we advance that further well-controlled RCTs are essential in the attempt to provide a reliable dose–response curve with applicability to the clinical scenario. To the best of our knowledge, a feasible plateau effect cannot be established to date, mainly considering that the study with the highest dose of TT has several biases and received 2 points for the Jadad score. The highest dose of TT supplementation tested was 12 g/d in patients with oligozoospermia . Regarding the dosage regimen for ED, TT supplementation varied from 400 to 750 mg/d for 1 to 3 months in patients with mild-to-moderate ED 9,12,21,23. Regarding the TT supplementation protocol, the dosage regimens varied from 400 mg to 12 g/day for 4 weeks to 3 months. Table 3 summarizes the studies included in the systematic review. Finally, 10 studies were qualified and selected for the presented systematic review (Figure 1).|In this review, you will learn the results of the clinical studies on this herbal ingredient. It's in MANY dietary supplements. Always consult a licensed healthcare professional before starting any medication, supplement regimen, or treatment plan. For maintaining your overall health, I would say a definite yes, but if you’re looking to boost testosterone specifically, there are better options available. So if you have low testosterone, or a diminished sex drive, tribulus might help normalize the imbalance. In general, some of the claims made by Tribulus terrestris supplement manufacturers aren’t really supported by scientific evidence.}

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